TOXOPLASMOSIS ( T.) Identification. Zoonotic disease caused by an о bligate презентация
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- 2. Historic reference. 1908 J.Nicolas and L. Manseaux in
- 3. The actuality of illness is determined by the following factors:
- 4. - absence for the doctors of common practice sufficient knowledge and
- 5. It is size from 2- 4 microns of width and to
- 7. The biotic cycle Т. consists from sexual and asexual reproduction
- 8. Mature trophozoite is divided on merozoites, which part again penetrate into
- 9. Oocyst together with feces of the cat gets in the external
- 11. The main intermediate hosts - rats and mice, which some time
- 12. A nuclear cell before destroy ( “false cyst”)
- 13. After destroy a cell Т. penetrate into other cell recycling developments.
- 15. PATHOMORPHOLOGY The pathological changes are found out in all bodies both
- 16. It is possible to detect granulomas, centers of a necrosis and
- 17. EPIDEMIOLOGY (zoonosis with peroral and vertical mode of infection)
- 18. CLINIC (incubation interval about 2 weeks) Distinguish 2 forms Т.
- 21. To frequency there is a combination of numbered mani-festations by an
- 22. Objective: - generalized lymphadenopathy - increase of a liver (50 %)
- 23. - eyes - chorioretinitis (1 %), uveitis, progressing myopia -
- 24. CONGENITAL Т. - arises only at primary infection by the pregnant
- 25. Signs of disease is possible to detect for child at once
- 26. But it can pass in the chronic or secondary - latent
- 27. DIFFERENTIAL DIAGNOSTICS will be carried out by : - Catscratch disease
- 28. LABORATORY DIAGNOSIS. 1.Microscopy smears CSF ( at congenital Т.) – xanthochromatic,
- 29. TREATMENT The antiparasitic therapy Will not be carried out:
- 30. for strengthen operation of pyrimethaminum: - clindamycin 300 mg
- 31. For the pregnant woman at immunological peaking without clinical manifestations -
- 32. PROPHYLAXIS The special attention accesses on group of hazard among the
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